A Review on Analytical Methods of Irbesartan and its Combinations in Pharmaceutical Dosage Forms

Author(s): Calamur Nagarajan Nalini*, Nivedhitha Mathivanan

Journal Name: Current Pharmaceutical Analysis

Volume 16 , Issue 8 , 2020

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Graphical Abstract:


Pharmaceutical analysis plays an indispensable role in various stages of drug pipeline including drug development, fabrication of formulation, stability studies and quality control. It is also used for characterizing the composition of different dosage forms in quantitative and qualitative ways. Comprehensive literature survey forms the foundation stone for the focused analysis of research activity. Irbesartan is a hypertension antagonist chiefly employed in the treatment of high blood pressure which is an Angiotensin II Receptor blocker. The multiple mixtures of various antihypertensive medicaments raise challenges in the method development and validation. A genuine venture is undertaken to compile the literatures related to the antihypertensive drug Irbesartan published in various peer reviewed journals. HPLC and UV spectrophotometry are the most preferred analytical techniques when compared to other methods. This present review provides an in-depth assortment of various analytical techniques published for Irbesartan and its combinations, which will help the researchers in their future endeavors.

Keywords: Analytical methods, irbesartan, antihypertensive, amlodipine, hydrochlorothiazide, pharmaceutical dosage.

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Article Details

Year: 2020
Page: [1020 - 1029]
Pages: 10
DOI: 10.2174/1573412915666190802164428
Price: $65

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