Synthesis of New C2-Symmetric Chiral Benzimidazole Derivatives Having Norbornene/Dibenzobarrelene Skeletons

Author(s): İrfan Çapan, Süleyman Servi*

Journal Name: Letters in Organic Chemistry

Volume 17 , Issue 10 , 2020

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Graphical Abstract:


Racemic dicarboxylic acids were synthesized from the Diels-Alder cycloaddition reactions which formed the dibenzobarrelene and norbornene skeletons. The pure enantiomers of these compounds were obtained using brucine as the chiral auxiliary. Novel C2-symmetric chiral benzimidazole derivatives were synthesized from the reaction of the diaminobenzene and enantiomeric dicarboxylic acids in the presence of boric acid.

Keywords: Norbornene, dibenzobarrelene, guanidine, benzimidazole, chiral resolution.

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Article Details

Year: 2020
Published on: 17 November, 2020
Page: [801 - 805]
Pages: 5
DOI: 10.2174/1570178616666190731105327
Price: $65

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