Knowledge of Pharmacists about Anti-epileptic Drugs in a Developing Country

Author(s): Mohammed Awad Osman Ali*, Esra Abdallah Abdalwahed Mahgoub, Mohammed Nimir, Kamil Mirghani Ali

Journal Name: Current Drug Safety

Volume 15 , Issue 1 , 2020

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Background: Pharmacists play an essential role in educating the epileptic patients about their disease and their medications. Improving the patient’s awareness may lead to improve their compliance and decrease drug-drug interaction and ultimately improve their quality of life.

Objective: This study aimed to assess the pharmacist’s knowledge about anti-epileptic drugs in Khartoum State, Sudan.

Methods: We conducted a descriptive cross-sectional study in Khartoum State, Sudan. Proportionate stratified sampling was used to determine the targeted Pharmacies, and all pharmacists who were present in the selected pharmacy at the time of data collection and fulfilled our selection criteria were included in the study. A structure closed-ended questionnaire was used to collect quantitative data from candidates.

Results: Majority of participants were female (66.9%), less than 30 years old (66.7%) and have less than 5 years of experience (62.1%). Unfortunately, the majority of the participants (85.3%) had poor knowledge, and only (14.7%) of them had good knowledge. Furthermore, the study revealed that age (p =.030), years of experience (p =.026) and the degree in pharmacy (p = .003) were significantly associated with knowledge level.

Conclusion: Majority of the pharmacists in Khartoum State have poor knowledge about anti-epileptic drugs. Further research is needed to investigate the actual factors behind this knowledge gap and to propose interventions to improve the pharmacist’s knowledge and practice aiming to improve the quality of health care provided to the patients.

Keywords: Pharmacists, epilepsy, drugs, anti-epileptics, khartoum state, drug-drug intraction.

Shawahna R, Atrash A, Jebril A, Khalaf A, Shaheen E, Tahboosh H. Evaluation of pharmacists’ knowledge of women’s issues in epilepsy: A cross-sectional study in Palestinian pharmacy practice. Seizure 2017; 46: 1-6.
[] [PMID: 28167358]
Koshy S. Role of pharmacists in the management of patients with epilepsy. Int J Pharm Pract 2012; 20(1): 65-8.
[] [PMID: 22236182]
McAuley JW, Chen AY, Elliott JO, Shneker BF. An assessment of patient and pharmacist knowledge of and attitudes toward reporting adverse drug events due to formulation switching in patients with epilepsy. Epilepsy Behav 2009; 14(1): 113-7.
[] [PMID: 18768168]
Roth Y, Neufeld MY, Blatt I, et al. An evaluation of pharmacist knowledge on treatment with antiepileptic drugs. Seizure 2016; 34: 60-5.
[] [PMID: 26731337]
Fogg A, Staufenberg EF, Small I, Bhattacharya D. An exploratory study of primary care pharmacist-led epilepsy consultations. Int J Pharm Pract 2012; 20(5): 294-302.
[] [PMID: 22953768]
Shawahna R, Atrash A, Jebril A, Khalaf A, Shaheen E, Tahboosh H. Pharmacists’ knowledge of issues in pharmacotherapy of epilepsy using antiepileptic drugs: A cross-sectional study in Palestinian pharmacy practice. Epilepsy Behav 2017; 67: 39-44.
[] [PMID: 28088050]
Dos Reis TM, Campos MSA, Nagai MM, Pereira LRL. Contributions of pharmacists in the treatment of epilepsy: A systematic review. Am J Pharm Benefits 2016; 8(3): e55-60.
Directorate General of Pharmacy. Annual Report 2016.
Israel GD. Determining sample size. University of Florida. 2012. Available from:
Harimanana A, Chivorakul P, Souvong V, Preux PM, Barennes H. Is insufficient knowledge of epilepsy the reason for low levels of healthcare in the Lao PDR? BMC Health Serv Res 2013; 13(1): 41.
[] [PMID: 23379720]
Meinardi H, Scott RA, Reis R, Sander JWAS. The treatment gap in epilepsy: The current situation and ways forward. Epilepsia 2001; 42(1): 136-49.
[] [PMID: 11207798]
Sir S, Mohamed E, Mahmoud AA, Ali AA. Barriers for implementation of pharmaceutical care practice in community pharmacies in Sudan. Khartoum Med J 2014; 7(1): 921-31.

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Article Details

Year: 2020
Published on: 03 February, 2020
Page: [32 - 37]
Pages: 6
DOI: 10.2174/1574886314666190729114946

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