Background: Obesity, diabetes, and associated diseases are increasing all over the world, and pose a
great burden on public health. According to the latest reports, 440 million people are suffering from diabetes.
Diabetes is caused by impaired ability to produce or respond to the hormone insulin consequently resulting in
Methods: Data used for this review was obtained by using PUBMED/MEDLINE (1987-2018). The main data
search terms were: Gentiana lutea, Gentiana lutea extract, Gentiana lutea constituents, obesity, diabetes mellitus,
Results: In the present review, we describe the potential of root powder of yellow gentian (Gentiana lutea) for the
prevention of obesity and diabetes including complications related to this disease.
Conclusion: Reasonably effective, low-cost alternatives could fulfill an important role for a large part of the
human population and could be of great value for the food market. Even a modest reduction of morbidity and
mortality with respect to this disease translates into millions of lives saved.