A liposome is a spherical vesicle composed of a bilayer of lipid with central
aqueous cavity. Liposomes are the first nano vesicular drug delivery carriers, which are
successfully translated into real-time clinical application and gained great potential in the
past 30 years. The characteristics of liposomes to encapsulate both hydrophilic and hydrophobic
drugs, their biocompatibility and biodegradability make it attractive nanocarriers
in drug delivery area. Apart from this, great technical advancement has been made to
develops second-generation liposomes named as stealth liposomes, cationic liposomes,
triggered release liposomes and ligand targeted liposomes. This led to widespread use of
liposomes in various areas including anticancer therapeutics, diagnostics and imaging
agents. Therefore, the presents review article made an extensive discussion of various
liposomes and its applications in cancer treatment.
Keywords: Phospholipids, Liposomes, ligand targeted liposomes, Cancer, Anticancer drug, and Doxil.
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