Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the global burden of disease study 2010. Lancet 2012; 380(9859): 2095-128.
Liu L, Wang D, Wong KS, Wang Y. Stroke and stroke care in China: Huge burden, significant workload, and a national priority. Stroke 2011; 42(12): 3651-4.
Goldstein LB, Adams R, Becker K, et al. Primary prevention of ischemic stroke. A statement for healthcare professionals from the Stroke Council of the American Heart Association. Circulation 2001; 103(1): 163-82.
Flossmann E, Schulz UG, Rothwell PM. Systematic review of methods and results of studies of the genetic epidemiology of ischemic stroke. Stroke 2004; 35(1): 212-27.
Ikram MA, Seshadri S, Bis JC, et al. Genomewide association studies of stroke. N Engl J Med 2009; 360(17): 1718-28.
Zhang ZZ, Xu GL, Zhu WS, et al. Chromosome 12p13 variants contribute to large artery atherosclerotic stroke risk in a Chinese population. J Neurol Sci 2015; 357(1-2): 58-62.
Matsushita T, Umeno J, Hirakawa Y, et al. Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population. J Hum Genet 2010; 55(7): 473-6.
Wang X, Zhang JY, Liu Y, Zhang YD. Relationship between nerve injury-induced protein gene 2 polymorphism and stroke in Chinese Han population. J Biomed Res 2011; 25(4): 287-91.
Wang L, Pan XD, Wang Y, et al. A preliminary study about the association of ninjurin-2 gene polymorphisms with large artery atherosclerotic ischemic stroke and the influence of atherosclerosis vascular bed. Chinese Journal of Neurology 2014; 47(2): 107-12.
Olsson S, Melander O, Jood K, Smith JG, Lovkvist H, Sjogren M, et al. Genetic variant on chromosome 12p13 does not show association to ischemic stroke in 3 Swedish case-control studies. Stroke 2011; 42(1): 214-6.
Bozpolat A, Unal E, Topaloglu T, et al. The relationship between the prognosis of children with acute arterial stroke and polymorphisms of CDKN2B, HDAC9, NINJ2, NAA25 genes. J Thromb Thrombolysis 2019; 47(4): 578-84.
Tong YQ, Zhan FX, Han JJ, et al. Lack of association between two key SNPs on chromosome 12p13 and ischemic stroke in Chinese Uyghur population. J Neurol Sci 2012; 323(1-2): 52-5.
Ding H, Tu X, Xu YJ, et al. No evidence for association of 12p13 SNPs rs11833579 and rs12425791 within NINJ2 gene with ischemic stroke in Chinese Han population. Atherosclerosis 2011; 216(2): 381-2.
Lotta LA, Giusti B, Saracini C, et al. No association between chromosome 12p13 single nucleotide polymorphisms and early-onset ischemic stroke. J Thromb Haemost 2010; 8(8): 1858-60.
Hsieh YC, Seshadri S, Chung WT, et al. Association between genetic variant on chromosome 12p13 and stroke survival and recurrence: a one year prospective study in Taiwan. J Biomed Sci 2012; 19: 1.
Tong YQ, Zhang YW, Zhang RL, et al. Association between two key SNPs on chromosome 12p13 and ischemic stroke in Chinese Han population. Pharmacogenet Genomics 2011; 21(9): 572-8.
Chen K, Xiao ZS, Hou SQ, et al. Strong association between the NINJ2 gene polymorphism and the susceptibility of stroke in Chinese Han population in Fangshan district. Beijing Da Xue Xue Bao 2010; 42: 498-502.
Zeng XT, Liu H, Chen X, Leng WD. Meta-Analysis Series IV: A quality evaluation tool for observational research. Chinese J Evidence-Bases Cardiovasc Med 2012; 4(4): 297-9.
Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 1539-58.
Cochran WG. The combination of estimates from different experiments. Biometrics 1954; 10: 101-29.
Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994; 50(4): 1088-101.
Kiene H, Kienle GS, von Schon-Angerer T. Bias in meta-analysis. Homeopathy 2006; 95(1): 54.
Toshiyuki Araki, Jeffrey Milbrandt. Ninjurin2, a novel homophilic adhesion molecule, is expressed in mature sensory and enteric neurons and promotes neurite outgrowth. J Neurosci 2000; 20(1): 187-95.
Li XM, Xian WC, Li XH. Association between the SNPs polymorphisms of Ninjurin2 and ischemic stroke. J Qiqihar Univ Med 2014; 35(10): 1415-6.
Zhang L, Sun H, Zhao Z, et al. Correlation between polymorphism of NlNJ2 and stroke in the han nationality of Yunnan province. Med Inform 2015; 28(11): 20.
Xie JJ, Gu L, Chen Q, Wu GL, Yan Y, Su L. Correlation study on 12p13 single nucleotide polymorphism rs12425791 and Chinese medical syndrome types in ischemic stroke patients of the han nationality. Chinese J Integr Trad West Med 2013; 33(1): 47-50.
Kong XL, Zhang L, Li JC. Relationship of NINJ2 gene polymorphism with ischemic stroke in Xi’an Area. J Clin Res 2017; 34(3): 498-501.
Gu L, Xie JJ, Chen Q, Wu GL, Yan Y, Su L. Relationship between NINJ2 gene single nucleotide polymorphism rs12425791 and ischemic stroke in Guangxi Han population. Journal of Clinical Neurology 2012; 25(5): 347-9.
Li BH, Zhang LL, Yin YW, et al. Association between 12p13 SNPs rs11833579/rs12425791 near NINJ2 gene and ischemic stroke in East Asian population: Evidence from a meta-analysis. J Neurol Sci 2012; 316(1-2): 116-21.
Gu L, Yan Y, Long JX, et al. The rs11833579 and rs12425791 polymorphisms and risk of ischemic stroke in an Asian population: A meta-analysis. Thromb Res 2012; 130(3): e95-e102.
Wang QP, Li DJ, Zhang YJ, et al. Association between single-nucleotide polymorphisms of rs11833579/rs12425791 in Ninjurin 2 gene and ischemic stroke in Chinese Han population: Evidence from a meta-analysis. Chinese J Neuromed 2017; 16(2): 167-73.
Lai LQ, Xian WC, Chen YS. Association of NINJ2 Gene 5′ upstream single-nucleotide polymorphisms with cerebral infarction. Chinese J Rehab Theor Pract 2015; 21(3): 315-9.
Wang L, Zhao C, Xia QX, Qiao SJ. Association between 12p13 SNP rs11833579 and ischemic stroke in Asian population: An updated meta-analysis. J Neurol Sci 2014; 345(1-2): 198-201.
International Stroke Genetics Consortium, Wellcome Trust Case- Control Consortium 2. Failure to validate association between 12p13 variants and ischemic stroke N Engl J Med 2010; 362(16): 1547-50.
Wang F, Hu CM, Zhang SY, et al. Association of Ninjurin-2 gene polymorphisms with large artery atherosclerotic ischemic stroke. J Med Mol Biol 2014; (6): 326-30.
Fox CS, Polak JF, Chazaro I, et al. Genetic and environmental contributions to atherosclerosis phenotypes in men and women: Heritability of carotid intima-media thickness in the Framingham Heart Study. Stroke 2003; 34(2): 397-401.
Ming D. Li, Rong Cheng, Jennie Z Ma, Gary E. Swan. A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction 2003; 98: 23-31.
Williams RR, Hunt SC, Hopkins PN, et al. Genetic basis of familial dyslipidemia and hypertension: 15-year results from Utah. Am J Hypertens 1993; 6(11): 319S-27S.
Medici F, Hawa M, Ianari A, Pyke DA, Lesile RD. Concordance rate for type II diabetes mellitus in monozygotic twins: Actuarial analysis. Diabetologia 1999; 42: 146-50.
Snieder H, van Doornen LJ, Boomsma DI. Dissecting the genetic architecture of lipids, lipoproteins, and apolipoproteins lessons from twin studies. Arterioscler Thromb Vasc Biol 1999; 19: 2826-34.
He J, Klag MJ, Wu Z, Whelton PK. Stroke in the People’s Republic of China. I. Geographic variations in incidence and risk factors. Stroke 1995; 26(12): 2222-7.
Polonikov A, Rymarova L, Klyosova E, et al. Matrix metalloproteinases as target genes for gene regulatory networks driving molecular and cellular pathways related to a multistep pathogenesis of cerebrovascular disease. J Cell Biochem 2019. [Epub ahead of print].
Ramazi S, Heydari-Zarnagh H, Goudarzian M, Khalaj-Kondori M, Bonyadi M. Thromboxane A synthase 1 gene expression and promotor haplotypes are associated with risk of large artery-atherosclerosis stroke in Iranian population. J Cell Biochem 2019; 120(9): 15222-32.
Pjević DM, Bumbaširevic BL, Vojvodic L, et al. Analysis of the association between polymorphisms within PAI-1 and ACE genes and ischemic stroke outcome after rt-PA therapy. J Pharm Pharm Sci 2019; 22(1): 142-9.
Shang XJ, Lin Y, Fang L, et al. Association analysis of two polymorphisms on chromosome 12p13 to cerebral infarction. Chinese Journal of Neurology 2011; 44(9): 613-8.