Syndrome of Supine Hypertension with Orthostatic Hypotension: Pathophysiology and Clinical Approach

Author(s): Aamir Ahmed, Mohammed Ruzieh*, Shaffi Kanjwal, Khalil Kanjwal

Journal Name: Current Cardiology Reviews

Volume 16 , Issue 1 , 2020

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Graphical Abstract:


This article is intended to provide guidance and clinical considerations for physicians managing patients suffering from supine hypertension with orthostatic hypotension, referred to as “SH-OH”. We review the normal physiologic response to orthostasis, focusing on the appropriate changes to autonomic output in this state. Autonomic failure is discussed with a generalized overview of the disease and examination of specific syndromes that help shed light on the pathophysiology of SH-OH. The goal of this review is to provide a better framework for clinical evaluation of these patients, review treatment options, and ultimately work toward achieving a better quality of life for patients afflicted with this disease.

Keywords: Orthostatic hypotension, supine hypertension, autonomic failure, dysautonomia, blood pressure, orthostatic posture.

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Article Details

Year: 2020
Published on: 16 June, 2019
Page: [48 - 54]
Pages: 7
DOI: 10.2174/1573403X15666190617095032
Price: $65

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