Background: In this review, different heterogeneous catalysts based on acid, base, metal
and enzymes are discussed for the synthesis of industrially relevant perfumes and flavor compounds.
These molecules are mainly produced by a variety of reaction pathways such as esterification, isomerization,
hydration, alkylation, hydrogenation, oxidation, etc. All these reactions are discussed thoroughly
for the synthesis of vital aromatic compounds. The review also summarizes various recent
technologies applied for designing new catalysts to obtain the maximum yield of the desired product.
Overall, this review highlights the green, clean and eco-friendly processes which can be industrially
accepted for the synthesis of perfumes, flavors and fragrances.
Objective: The objective of the current review was to emphasize on the synthesis of industrially important
perfumes and flavor molecules such as α-terpineol, cyclohexyl esters, thymol, raspberry ketone,
etc. using heterogeneous catalysts.
Results: Three hundred and eight papers are reported in this review, the majority of which are on heterogeneous
catalysis for the synthesis of molecules which impart flavor or possess perfumery characteristics.
Among all, the preparation of esters is highlighted as they represent an imperative functional
group in aroma chemicals.
Conclusion: The review confirms the need for heterogeneous catalysis in pollution-free and costeffective
synthesis of flavor and perfumery compounds.