Sex Steroids and Apoptosis In Skeletal Muscle: Molecular Mechanisms

Sex Steroids and Apoptosis In Skeletal Muscle: Molecular Mechanisms

This monograph focuses on the actions exerted by sex hormones, 17β-estradiol and testosterone, in skeletal muscle tissue. An important consideration of this volume is the fact that both estrogen ...
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Subcellular Localization Of Estrogen Receptors

Pp. 63-72 (10)

DOI: 10.2174/9789811412363119010005

Author(s): Lorena M. Milanesi

Abstract

It is well established that estrogens elicit a variety of rapid effects in many tissues in addition to their actions on gene expression in the cell nucleus after Estrogen Receptors (ERs) dimerization and DNA-binding through their EREs. In this chapter we describe tissue distribution, subcellular localization, targets and roles of classical and non-classical ERs.

Keywords:

Estrogen Receptor, ER α and β, Golgi, Mitochondria, Subcellular Localization.