Natural Products for the Treatment of Neurodegenerative Diseases

Author(s): Ze Wang, Chunyang He, Jing-Shan Shi*

Journal Name: Current Medicinal Chemistry

Volume 27 , Issue 34 , 2020

Become EABM
Become Reviewer

Abstract:

Neurodegenerative diseases are a heterogeneous group of disorders characterized by the progressive degeneration of the structure and function of the central nervous system or peripheral nervous system. Alzheimer's Disease (AD), Parkinson's Disease (PD) and Spinal Cord Injury (SCI) are the common neurodegenerative diseases, which typically occur in people over the age of 60. With the rapid development of an aged society, over 60 million people worldwide are suffering from these uncurable diseases. Therefore, the search for new drugs and therapeutic methods has become an increasingly important research topic. Natural products especially those from the Traditional Chinese Medicines (TCMs), are the most important sources of drugs, and have received extensive interest among pharmacist. In this review, in order to facilitate further chemical modification of those useful natural products by pharmacists, we will bring together recent studies in single natural compound from TCMs with neuroprotective effect.

Keywords: Natural Products, Neurodegenerative diseases, Alzheimer`s disease, Parkinson`s disease, Spinal Cord Injury, CDM.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 27
ISSUE: 34
Year: 2020
Page: [5790 - 5828]
Pages: 39
DOI: 10.2174/0929867326666190527120614
Price: $95

Article Metrics

PDF: 10