Succinic Acid Production as Secondary Metabolite from Bacillus megaterium ELI24

Author(s): Aurelio Ortiz, Estibaliz Sansinenea*

Journal Name: The Natural Products Journal

Volume 10 , Issue 2 , 2020

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Graphical Abstract:


Background: Succinic acid can be used as a precursor of many industrially important chemicals and has an extensive application range to apply in different industrial areas, such as pharmaceutical and food industry.

Objective: In this work, we isolated a strain of B. megaterium which produces succinic acid in optimized czapek medium for its production.

Methods: A study of the production of this organic acid was realized in different media adding insoluble phosphate sources to czapek medium.

Results: Two Bacillus strains ELI 24 and ELI30 that were isolated from soil in Mexico were fully characterized as Bacillus megaterium and B. thuringiensis. B. megaterium ELI 24 was proved to secrete succinic acid which was clearly identified by spectroscopic methods, such as 1H and 13C NMR, and X-ray analysis.

Conclusion: This organic acid could improve the solubility of insoluble phosphate, which could help in the growth of plants.

Keywords: Bacillus megaterium, secondary metabolites, succinic acid, phosphate solubilizing bacteria, ELI 24, spectroscopic methods.

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Article Details

Year: 2020
Page: [153 - 157]
Pages: 5
DOI: 10.2174/2210315509666190410153811
Price: $25

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