Background: Scutellariae Radix (Huangqin) is commonly processed into 3 products for
different clinical applications. However, a simple analytical method for quality control has rarely been
reported to quickly estimate the degree of processing Huangqin or distinguish differently processed
products or unqualified Huangqin products.
Objective: To study a new strategy for quality control in the processing practice of Huangqin.
Methods: Seven kinds of flavonoids that mainly exist in Huangqin were determined by HPLC-DAD.
Chromatographic fingerprints were established to study the variation and discipline of the 3 processed
products of Huangqin. PCA and OPLS-DA were used to classify differently processed products of
Results: The results showed that baicalin and wogonoside were the main components in the crude and
the alcohol Huangqin herb while baicalein and wogonin mainly existed in carbonized Huangqin. The
results of mathematical statistics revealed that the processing techniques can make the quality of medicinal
materials more uniform.
Conclusion: This multivariate monitoring strategy is suitable for quality control in the processing of