Atherosclerosis provokes a continuous worsening of affected vessels causing a blood flow diminution
with several complications and with clinical manifestations that generally appear in advanced phases of the illness.
Hence, the conventional therapies are not enough because the atherosclerotic injuries are often irrevocable.
For this reason, emerges the necessity to implement smart ways of drug supply and develop new therapeutic
targets that decrease the advance atherosclerotic lesion. It results due to particular interest to use new tools for
prevention, diagnosis, and treatment of this cardiovascular disease, thus concentrating our attention to accomplish
better management on the immune system. Finally, this mini-review highlights the most recent knowledge about
nanotechnology as a robust, novel and promissory therapeutic option applied to atherosclerotic pathology, nevertheless,
we also alert for possible issues associated with their use.