Omic-technologies (genomics, transcriptomics, proteomics and metabolomics)
have become more important in current medical science. Among them, it is metabolomics that
most accurately reflects the minor changes in body functioning, as it focuses on metabolome –
the group of the metabolism products, both intermediate and end. Therefore, metabolomics is
actively engaged in fundamental and clinical studies and search for potential biomarkers. The
biomarker could be used in diagnostics, management and stratification of the patients, as well
as in prognosing the outcomes. The good example is gynecology, since many gynecological
diseases lack effective biomarkers. In the current review, we aimed to summarize the results
of the studies, devoted to the search of potential metabolomic biomarkers for the most common
Keywords: Metabolomics, biomarkers, gynecology, uterine cervical neoplasms, ovarian neoplasms, endometriosis,
polycystic ovary syndrome, leiomyoma.
Draj, H.A.; Abbas, A.A.; Abdullah, T.H. Serum levels of glycodelin a and soluble intracellular adhesion molecule-1 as biomarkers for endometriosis. Iraqi JMS, 2017, 15(4), 345-349.
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