Nature has been a source of a wide range of products being utilized for the treatment of
various diseases like malaria, cancer, diabetes etc. Among these, cancer is emerging as a leading cause
of deaths worldwide and the development of cross-resistance to already established drugs increases the
need for novel anticancer drugs. To discover novel anticancer molecules, it is a necessity to unearth the
molecules which can act as anticancer agents. Taking natural products in vision, phytoconstituents like
terpenoids, flavones, glycosides and alkaloids might act as a major source of lead molecules.
Considering the anticancer prospectives of phytoconstituents, different unknown lead molecules are
summarized in this review. The present review highlights the representative studies of plant-based
anticancer agents which are classified as per their phytochemical nature. Furthermore, important key
points along with important structure-activity relationships points regarding selected lead molecules are
Keywords: Abietane, Fucoxanthin, Obovatol, Phytoconstituents, Anticancer, Lead molecules, Terpenoids.
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