Background: Nanotechnology-based drug delivery approach has emerged as a promising
field, where different kinds of formulations are developed for therapeutic applications. Inflowing of
nanomedicine developed through various biomaterials appears to be a game changer in the domain of
pharmaceutical and biotechnological industries. Nanomedicines propose to overcome the major constraints
of conventional medicine of low solubility and stability, non-adequate pharmacokinetic profiles
and side effects.
Objectives: Mesoporous Silica Nanoparticles (MSNs) have garnered significant attention in biomedical
applications for its multifunctionality. The porous structure of MSNs provides the opportunity for
heavy drug loading, controlled release and ligand functionality. From last decades, a lot of interest has
been generated owing to the better drug delivery attributes of MSNs to introduce unique biological
effects for its suitable therapeutic application.
Methods: The review article gives an insight into the current advancement of usage of MSNs in drug
delivery for cancer, non-cancer and biosensors based biomedical applications along with technology
that is protected by patents.
Conclusion: The future success of MSNs is widened because of their valuable characteristic that
easily combines with various functionalities which would display enormous potential translational