Background: Gastric cancer is the second leading cause of cancer death worldwide.
Aims: In the benign and malign gastric pathologies, we measured the Apparent Diffusion Coefficient
(ADC) value from the thickened section of the stomach wall. We assessed the diagnostic value
of ADC and we wanted to see whether this value could be used to diagnose gastric pathologies.
Study Design: This study has a prospective study design.
Methods: A total of 90 patients, 27 with malign gastric pathologies 63 with benign gastric pathologies
with Gastric Wall (GW) thickening in multidector CT, were evaluated by T2 weighted axial
MR imaging and Diffusion-Weighted Imaging (DWI). Measurements were made both from the
thickened wall and from the normal GW. Also, a new method called GW/spine ADC ratio was performed
in image analysis. The value found after ADC measurement from the GW was proportioned
to the spinal cord ADC value in the same section.
Results: The ADC values measured from the pathological wall in patients with gastric malignancy
(1.115 ± 0.156 x10-3 mm2/s) were significantly lower than the healthy wall measurements (1.621 ±
0.292 × 10-3 mm2/s) and benign gastric diseases (1.790± 0.359 x10-3 mm2/s). GW/spine ADC ratio
was also lower in gastric malignancy group.
Conclusion: ADC measurement in DWI can be used to distinguish between benign and malign gastric