Abdominal tuberculosis is difficult to diagnose due to low sensitivity of microbiological
tests and the low histological yield. Satisfactory response to therapy has long been used a criteria
for the diagnosis of abdominal tuberculosis. However, the appropriate definitions of response
to therapy in abdominal tuberculosis have remained unclear. Recent evidence suggests that mucosal
healing of ulcers at the end of therapy or at two months (early mucosal response) is a helpful
criteria of response to therapy. This also helps in exclusion of multidrug resistant tuberculosis and
alternative diagnosis like Crohn’s disease. Further limited literature suggests the use of some biomarkers
like C-reactive protein in the follow-up of patients with peritoneal or intestinal tuberculosis.
Keywords: Peritoneal tuberculosis, ulcer healing, cocoon, intestinal tuberculosis, strictures, pancreatic tuberculosis, hepatic
Mandavdhare, H.S.; Singh, H.; Sharma, V. Recent advances in the diagnosis and management of abdominal tuberculosis. EMJ Gastroenterol., 2017, 6(1), 52-60.
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