Background: Sri Lanka offers a huge diversity of flora with a large proportion of those
being endemic to the island. Both the endemic and native plants species serve as a rich bank of
Method: In this study, “Sri Lankan Flora” an online web-based information system of phytochemical
compounds isolated from the flora of Sri Lanka was proposed.
Results: The database contained 3D structures of those compounds, calculated quantitativestructure-
activity relationship (QSAR) data and the GROMOS 54a7 force field parameters for each
and every compound. The manually curated chemical structures, activities and force field parameters
provide a possible direct avenue for computer-aided drug discovery. The present study is a
continuing project with a wider goal of building up a database, not only for assisting the computeraided
drug designing process, but also for other chemical applications, as the database includes
structural, physical, chemical and dynamic properties of chemical compounds of the flora of Sri
Lanka. The database is freely accessible at http://science.cmb.ac.lk/tools/slflora.