Study the Effect of PG E1 and PGF2α on Male Rat Reproductive Functions

Author(s): Ali Esmail Al Snafi*, Khalid G. Al-Fartosi, Zainab Qasim Al-Yasiry

Journal Name: Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Under Re-organization)
(Formerly Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents)

Volume 18 , Issue 1 , 2018

Graphical Abstract:


Background: This research was performed to investigate the effects of prostaglandins on the sexual functions of albino male rats. The effects of prostaglandins on LH, FSH, testosterone secretion and semen quality of the male rats were investigated. PGE1 induced a significant decline in the level of LH, FSH and testosterone levels. PGE1 also induced significant decline in the testis, epididymal and seminal vesicle weights.

Conclusion: Furthermore, PGE1 caused significant reduction in sperm count, and significant decline in the viable and malformed sperm percent. However, PGF2α did not affect these parameters.

Keywords: Reproduction, PGE1 , PGF2α, male, rats, LH, FSH, testosterone.

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Article Details

Year: 2018
Published on: 19 September, 2018
Page: [76 - 79]
Pages: 4
DOI: 10.2174/1871522218666180417151333
Price: $58

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