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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Review Article

Role of Biomacromolecules in Biomedical Engineering

Author(s): Juan M. Ruso and Natalia Hassan*

Volume 18, Issue 14, 2018

Page: [1171 - 1187] Pages: 17

DOI: 10.2174/1568026618666180816155917

Abstract

Biomacromolecules structures and their interaction between different systems have been extensively studied in the last years. Nevertheless, in the medicinal context, it has not been studied deeply. For this reason, the interest to investigate the behavior of different biomacromolecules such us proteins, organelles, phospholipids, etc. with soft materials has opened new research lines. Computational and experimental methodologies have tried to answer different questions that have been difficult to solve, due to the complexity of the phenomenon, as an example, competition between biomacromolecules and soft materials for a specific organ. In this review, we would like to demonstrate how soft materials influence the biomacromolecules structures and how to change their response, biodistribution and also biocompatibility for future applications.

Keywords: Biomacromolecules, Immune response, Metabolism, Organelles, Phospholipids, Proteins.

Graphical Abstract

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