Tissue engineering provides solutions that require medicine to restore damaged tissues or
even complete organs. This discipline combines biologically active scaffolds, cells and molecules; being
the addition of nanoparticles into the scaffolds, one of the techniques that is attracting more interest
these days. In this work, Hydroxyapatite Nanorods (HA) were added to the network of Gelatin hydrogel
(GE), and the particular properties resulting from their interaction were studied. Specifically, viscoelastic
properties were characterized as a function of gel and nanoparticle concentration, varying ratios and
temperatures. Oscillatory Time Sweeps (OTS) provided the necessary information about how the timeresolved
material property/structure alteration. A wide variety of Continuous Flow Tests and Frequency
Sweeps were used to describe the mechanical properties of the material, proving that the presence of
nanoparticles led to a reinforcement of the gel network, mechanical stiffness and strength. The thixotropic
nature of the gels was also evaluated and the most common theoretical models were described
and commented. The attributes inferred from the data, showed a material that can allow the natural
growth of bone tissue whilst withstanding properly the mechanical efforts; resulting in a material with
an outstanding suitability to be used in regenerative medicine.
Keywords: Hydroxyapatite Nanorods, Cells, Medicine, Molecules, Nanoparticles, Organs.
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