Overview of the Recent Advances in Pathophysiology and Treatment for Autism

Author(s): Hamidreza Famitafreshi, Morteza Karimian*

Journal Name: CNS & Neurological Disorders - Drug Targets
(Formerly Current Drug Targets - CNS & Neurological Disorders)

Volume 17 , Issue 8 , 2018

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Graphical Abstract:


Background & Objective: Autism is a developmental disorder that manifests itself in early childhood. Autism is characterized by inability to acquire social skills, repetitive behaviors and failure of speech and nonverbal communication development. Recent studies have shown that genetic mutations occur in majority of individuals with autism. These mutations cause a variety of disorders that ultimately lead to brain disorders. It is noteworthy that all mutations do not follow the same pattern. They encompass various kinds of mutations. Autism needs to be treated during childhood as untreated patients usually do not progress to the later stages of development. In this regard, many studies have been performed and numerous treatments have been proposed to improve the outcome of this disease.

Conclusion: In this review, we have discussed new advancements made in understanding the pathophysiology of autism. Furthermore, we have also discussed new treatments which have been proposed and have successfully translated affected children. Overall, it is concluded that new advances have largely helped these patients.

Keywords: Autism, nutrition, immune system, mutation, gut-brain, brain stimulation.

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Article Details

Year: 2018
Published on: 02 October, 2018
Page: [590 - 594]
Pages: 5
DOI: 10.2174/1871527317666180706141654
Price: $65

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