Pharmacological Effects and Chemical Constituents of Bupleurum

Author(s): Peng Sun, Yijie Li, Sheng Wei, Tingting Zhao, Yang Wang, Chunhong Song, Ling Xue, Fushun Wang, Lingyun Xiao, Jibiao Wu, Mingqi Qiao*

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 19 , Issue 1 , 2019


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Abstract:

Radix Bupleuri has been used in traditional Chinese medicine for thousands of years, with confirmed curative effects. This plant is also used in healthy food and cosmetics. A recent increase in studies of Radix Bupleuri’s chemical constituents (mainly comprising flavonoids, lignins, phenyl propanol derivatives, triterpenoid saponins, and volatile oils) and pharmacological effects motivates the aim of the present study: to review the chemical components and pharmacological effects of Radix Bupleuri. Our review found that Radix Bupleuri exhibits diverse pharmacological effects. More than 281 components have been isolated from Radix Bupleuri, including 15 flavonoids, 430 lignins, 12 phenyl propanol derivatives, 66 triterpenoid saponins, and 158 volatile oils.

Keywords: Radix Bupleuri, pharmacological action, chemical composition, Chinese medicine, flavonoids, phenyl propanol derivatives, triterpenoid saponins, volatile oils.

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Article Details

VOLUME: 19
ISSUE: 1
Year: 2019
Published on: 06 December, 2018
Page: [34 - 55]
Pages: 22
DOI: 10.2174/1871520618666180628155931
Price: $65

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