Recently Applications of tert-butyl Nitrite in Organic Synthesis-Part I

Author(s): Nader Ghaffari Khaligh*

Journal Name: Current Organic Chemistry

Volume 22 , Issue 11 , 2018

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Graphical Abstract:


This mini-review will describe the recent applications of tert–butyl nitrite (TBN) in organic synthesis. Due to its unique structural feature and wide application, TBN holds a prominent and great potential in organic synthesis. Since the applications of TBN is too wide and developments have been too fast, Part-I of the present mini-review has surveyed the studies carried out to date in three areas viz. aerobic oxidation, annulation, and diazotization, which is demonstrated by the work outlined in this mini-review. The mechanisms of these transformations will be briefly described in this mini-review. TBN has been utilized in other organic transformations, such as nitrogenation, nitrification, nitrosylation, multifunctionalization, nitrodecarbocyclization, nitro-aminoxylation and etc. which will be presented as part- II in mid-2018.

Keywords: tert-Butyl nitrite, organic synthesis, aerobic oxidation, annulation, diazotization, mechanism.

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Article Details

Year: 2018
Page: [1120 - 1138]
Pages: 19
DOI: 10.2174/1385272822666180430124840
Price: $58

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