Title:Characteristics and Trends of C-H Activation Research: A Review of Literature
VOLUME: 15 ISSUE: 6
Author(s):Yanqi Wu, Yuehua Wan and Fengzhi Zhang*
Affiliation:Institute of Information Resource, Zhejiang University of Technology, Hangzhou, 310014, Institute of Information Resource, Zhejiang University of Technology, Hangzhou, 310014, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014
Keywords:C-H activation, transition metal, catalysis, cross-coupling, bibliometrics, SCI, author keywords analysis.
Abstract:Background: C-H activation has attracted great interests over the past two decades, which resulted
in an explosive growth in both quality and quantity of published papers related to this topic.
Objective: In this review, a bibliometric analysis was performed to evaluate the publications in this field from
1996 to 2015 based on the Science Citation Index (SCI) Expanded database. This work presented a detailed
overview of C-H activation from aspects of types of articles, citations, h-indices, languages, years, journals,
institutions, countries and author keywords.
Conclusion: The results showed that the USA took the leading position in this research field, followed by P. R.
China and German. Chinese Academy of Science had the most publications and the highest h-index, Scripps
Research Institute won the first place as far as the highest average citation per paper is concerned. Organometallics,
Angewandte Chemie International Edition and Journal of the American Chemical Society were the most
productive journals in this field, and Chemistry was the most frequently used subject category. Keywords
analysis indicated that most research focused on the Palladium, Rhodium and Copper catalyzed cross-coupling
synthetic method development for the heterocycle synthesis. The research about exploring the asymmetric C-H
functionalization, mechanism investigation and solving the regioselectivity issue is the development trend in
this area.