New Trends in Electrochemical Sensors Modified with Carbon Nanotubes and Graphene for Pharmaceutical Analysis
Pp. 249-301 (53)
Burcin Bozal-Palabiyik, Burcu Dogan-Topal, Sibel A. Ozkan and Bengi Uslu
Recently, carbon nanotubes (CNT) and graphene have been chosen as
electrode material due to their unique mechanical, optical and electrical properties.
These carbon-based materials are used to facilitate electrode reaction and produce an
electrocatalytic effect. Moreover, a plethora of literature has emerged concerning CNT
and graphene being employed to obtain a more selective and sensitive analysis. This
chapter reviews this emerging literature focusing on drug analysis from pharmaceutical
dosage forms and biological matrices. To achieve this, first, there is a summary of the
basic properties, synthesis, characterization, electrode preparation and
advantages/limitations of these materials, and then a selection of the literature from
2010 to 2017 is presented, which summarizes the type of electrode, electrochemical
techniques, peak potential of drug compounds and the limit of detection values.
Amperometry, Analysis, Buffer solution, Carbon nanotube,
Chronoamperometry, Chronocoulometry, Composite material, Cyclic
voltammetry, Determination, Drug, Electrochemistry, Electrochemical sensors,
Graphene, Graphene oxide, Impedance spectroscopy, Modified electrodes,
Nanosensors, Pharmaceutical formulation, Potentiometry, Stripping voltammetry.
Faculty of Pharmacy, Department of Analytical Chemistry, Ankara University, 06100, Tandogan, Ankara, Turkey.