Direct Methanol Catalytic Fuel Cell, for Measuring Ethanol Contents in Pharmaceutical Tinctures

Author(s): Mauro Tomassetti*, Riccardo Angeloni, Sergio Marchiandi, Mauro Castrucci, Elisabetta Martini, Luigi Campanella.

Journal Name: Current Analytical Chemistry

Volume 16 , Issue 2 , 2020

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Abstract:

Objective: In order to test real direct applicability for analytical purposes, a small and simple direct methanol (or ethanol) catalytic, enzymatic or non-enzymatic fuel cell (DMFC) was used for the analysis of ethanol-based pharmaceutical tinctures; a detailed experimental study was conducted on five different pharmaceutical tinctures available at drugstores.

Results: The results obtained using both enzymatic and non-enzymatic devices were compared with those obtained by analyzing the same pharmaceutical samples with a conventional catalase biosensor. Finally, the results were compared with the nominal values provided by manufacturing firms.

Conclusion: The correlations between the different experimental and nominal values considered were good in general or satisfactory and the applied statistical tests (f-test and t-test) were also very comforting. At the end of the study, the use of enzymatic DMFC proved to be better than non- enzymatic DMFC devices, because it requires shorter analysis times.

Keywords: Direct methanol catalytic fuel cell (DMFC), pharmaceutical tinctures, ethanol, enzyme, catalytic reaction, catalase biosensor.

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Article Details

VOLUME: 16
ISSUE: 2
Year: 2020
Page: [184 - 194]
Pages: 11
DOI: 10.2174/1573411014666180418160300
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