Title:Quantitative Vascular Evaluation: From Laboratory Experiments to Point-of-Care Patient (Clinical Approach)
VOLUME: 14 ISSUE: 2
Author(s):Ricardo L. Armentano* and Leandro J. Cymberknop
Affiliation:Cardiovascular Engineering Lab, GIBIO, Universidad Tecnologica Nacional, Buenos Aires, Cardiovascular Engineering Lab, GIBIO, Universidad Tecnologica Nacional, Buenos Aires
Keywords:Vascular function, hypertension, flow-mediated dilation, central pressure, stiffness, vascular age.
Abstract:To enhance the efficiency of patient-specific risk stratification and diagnosis, an
assessment of arterial structural and functional changes associated to a vascular disease in both
early and advanced stages have been proposed, with the objective of limiting the progression or
revert vascular alterations. In this connection, an interdisciplinary international partnership made up
by research institutions from France, Argentina, Uruguay and Spain was established, with the
objective of contributing to the evaluation and follow-up of factors involved in the physiopathology
of cardiometabolic diseases and human aging. Several studies, such as the effect of hypertension in
large arteries, alterations in arterial wall viscosity, stiffness and inertia, endothelial function and vascular
reactivity, cardiovascular risk improvement, vascular age assessment and cryografts vascular
response evaluation were carried out as a result of this international collaboration during the last
twenty-five years.
