Vascular research in end-stage renal diseases is an interesting field in which the characterization
of arterial stiffness proved to be valuable to predict morbidity and mortality. Particularly,
patients on renal replacement therapy have been reported to have significant increases in arterial
stiffness and cardiovascular mortality. The clinical relevance of the measurement of arterial stiffness
is linked to therapeutical and preventive interventions. The purpose of this work is to analyze
the results of the scientific research in the field of arterial stiffness, in which hemodialyzed patients
were involved, emphasizing on clinical and in-vitro research carried out by our group compared to
contributions previously reported in the specialized literature. These investigations are necessary to
improve diagnostic strategies and monitor the arterial response to therapeutical interventions in
chronic kidney disease.
Keywords: Arterial stiffness, aortic stiffness, pulse wave velocity, hemodialysis, vascular access, chronic kidney disease.
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