Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards

Author(s): Justine P.R. Oliveira*, H. Ivan Melendez-Ortiz, Emilio Bucio, Patricia Terra Alves, Mayara Ingrid Sousa Lima, Luiz Ricardo Goulart, Monica B. Mathor, Gustavo H.C. Varca, Ademar B. Lugao

Journal Name: Current Topics in Medicinal Chemistry

Volume 18 , Issue 4 , 2018

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Graphical Abstract:


Safety and biocompatibility assessment of biomaterials are themes of constant concern as advanced materials enter the market as well as products manufactured by new techniques emerge. Within this context, this review provides an up-to-date approach on current methods for the characterization and safety assessment of biomaterials and biomedical devices from a physical-chemical to a biological perspective, including a description of the alternative methods in accordance with current and established international standards.

Keywords: Biomaterials, Physico-chemical characterization, Biocompatibility, In silico, In vitro, In vivo, Ex vivo, Alternative methods, International standards.

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Article Details

Year: 2018
Published on: 10 April, 2018
Page: [256 - 274]
Pages: 19
DOI: 10.2174/1568026618666180410151518
Price: $65

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