Clinico-epidemiological Study of Morphea from a Tertiary Care Hospital

Author(s): Tasleem Arif*, Mohammad Adil, Syed S. Amin, Mohammad Tahseen, Konchok Dorjay, Mohd. Mohtashim, Manu Singh, Roopal Bansal, Dinesh Raj

Journal Name: Current Rheumatology Reviews

Volume 14 , Issue 3 , 2018

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Graphical Abstract:


Introduction: Morphea is an uncommon disease that presents with skin induration and sclerosis. The disease is common in Caucasians and there are few studies describing the clinicoepidemiological profile of these patients from the Indian subcontinent.

Methods: This prospective study was conducted during a three year period from June 2014 to May 2017. All patients of morphea presenting to the dermatology outpatient department were evaluated for parameters like age, sex, duration, age of onset, clinical subtype and possible disease associations and triggering factors. The data was analysed, tabulated and mean, standard deviation and percentages calculated.

Results: 47 patients were incorporated into the study. These comprised of 10 (21.28%) males and 37 (78.72%) females. The average age of the patients was 23.92 ± 12.07 years with a mean age of onset being 22.13 ± 12.51 years. 22 (46.80%) patients presented within one year of onset of disease. Plaque morphea was the commonest type seen in 31 (65.96%) patients followed by linear morphea in 9 (19.15%) patients. We found preceding trauma in 3 patients and morphea developed following herpes zoster and intramuscular injection in one patient each.

Conclusion: Morphea is an uncommon disease that is seen predominantly in females and young individuals. Circumscribed plaque morphea is the commonest variant. Certain predisposing factors like trauma can precede it.

Keywords: Induration, linear morphea, plaque morphea, trauma, sclerosis, collagen.

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Article Details

Year: 2018
Published on: 10 October, 2018
Page: [251 - 254]
Pages: 4
DOI: 10.2174/1573397114666180410115553
Price: $65

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