Advances in Organic Synthesis

Advances in Organic Synthesis

Volume: 8

Indexed in: Scopus, EBSCO, Ulrich's Periodicals Directory

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities ...
[view complete introduction]

US $

*(Excluding Mailing and Handling)

Advancements in Ionic Liquids for the Formation of Morita Baylis-Hillman Adducts

Pp. 224-254 (31)

Gitanjali Jindal, Navneet Kaur and Subodh Kumar


The reactions involving the carbon-carbon bond formation are the most significant and fundamental reactions in synthetic organic chemistry. Amongst such various types of reactions, Morita Baylis-Hillman (MBH) reaction has become one of the most constructive and popular routes for the production of functionalized molecules with vast utility and prospective. This reaction involves coupling of the activated alkenes with a variety of aldehydes under catalytic influence of tertiary bicyclic amines, phosphines or ionic liquids. The present significance of this reaction is credited to the fact that it leads to one-pot atom-economical construction of carbon-carbon bonds providing multifunctional molecules. Recently, ionic liquids are most extensively used for the synthesis of adducts of this reaction. This review is presented by the purpose of summarizing the various advances in ionic liquids and their use in this reaction.


Activated alkenes, Aldehydes, Atom-economy, Chirality, DABCO, DBU, DMAP, Green chemistry, Imidazole, Ionic liquids, Microwave irradiation, Morita-Baylis-Hillman reaction, Multifunctional, Phosphine, Quinuclidine, Recyclable, Solvent-free, Tertiary-amine, Triazole.


Department of Chemistry, Panjab University, Chandigarh, Punjab, India.