Adverse Effects of Non-Stimulant ADHD Drugs: Atomoxetine, Alpha-Agonists

Author(s): Myrtha Gregoire-Bottex*, Katherine Soe

Journal Name: Current Psychopharmacology

Volume 7 , Issue 1 , 2018

Become EABM
Become Reviewer

Graphical Abstract:


Background: Attention-deficit/hyperactivity disorder (ADHD) is a widespread diagnosis that affects many children and adolescents’ ability to function and succeed in academics, socially, or other situations. Non-stimulant medications have become widely utilized in this population, especially in stimulant-resistant individuals, whether due to poor efficacy or intolerance of side effects. However, these, too, harbor their own side effect profiles, including cardiovascular and sleep or energy level disturbances.

Objectives: We review the literature in discussion of the presentation and management of these adverse events for non-stimulant medications for ADHD, with a particular focus on atomoxetine and alpha agonists guanfacine and clonidine.

Conclusion: Non-stimulants are for the most part well tolerated but monitoring for cardiac and sleep difficulty is warranted.

Keywords: Mental health, children and adolescents, psychopharmacology, ADHD, attention deficit disorder, atomoxetine, alpha agonists.

Rights & PermissionsPrintExport Cite as

Article Details

Year: 2018
Page: [11 - 14]
Pages: 4
DOI: 10.2174/2211556007666180328150248
Price: $65

Article Metrics

PDF: 29
HTML: 10
PRC: 1