Abstract
Recently, the marine-derived Aspergillus present as producers of a large number of structurally novel secondary metabolites. Some of these metabolites have shown antitumor, antimicrobial, anti-inflammatory, antioxidant and enzymatic activities, and may be promising resources for new therapeutic drugs. This review sums up 232 new bioactive metabolites from the marine-derived Aspergillus with classification through their biological activities and chemical structures in 2006-2016. Besides, structure-activity relationships of some compounds are explored.
Keywords: Marine-derived Aspergillus, metabolites, cytotoxic, antimicrobial, antioxidant, enzymatic activities, structureactivity.
Mini-Reviews in Medicinal Chemistry
Title:New Bioactive Metabolites from the Marine-derived Fungi Aspergillus
Volume: 18 Issue: 13
Author(s): Kui-Wu Wang *Pei Ding
Affiliation:
- Department of Applied Chemistry, School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018,China
Keywords: Marine-derived Aspergillus, metabolites, cytotoxic, antimicrobial, antioxidant, enzymatic activities, structureactivity.
Abstract: Recently, the marine-derived Aspergillus present as producers of a large number of structurally novel secondary metabolites. Some of these metabolites have shown antitumor, antimicrobial, anti-inflammatory, antioxidant and enzymatic activities, and may be promising resources for new therapeutic drugs. This review sums up 232 new bioactive metabolites from the marine-derived Aspergillus with classification through their biological activities and chemical structures in 2006-2016. Besides, structure-activity relationships of some compounds are explored.
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Cite this article as:
Wang Kui-Wu *, Ding Pei , New Bioactive Metabolites from the Marine-derived Fungi Aspergillus, Mini-Reviews in Medicinal Chemistry 2018; 18 (13) . https://dx.doi.org/10.2174/1389557518666180305160856
DOI https://dx.doi.org/10.2174/1389557518666180305160856 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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