New Bioactive Metabolites from the Marine-derived Fungi Aspergillus

Author(s): Kui-Wu Wang*, Pei Ding

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 18 , Issue 13 , 2018

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Abstract:

Recently, the marine-derived Aspergillus present as producers of a large number of structurally novel secondary metabolites. Some of these metabolites have shown antitumor, antimicrobial, anti-inflammatory, antioxidant and enzymatic activities, and may be promising resources for new therapeutic drugs. This review sums up 232 new bioactive metabolites from the marine-derived Aspergillus with classification through their biological activities and chemical structures in 2006-2016. Besides, structure-activity relationships of some compounds are explored.

Keywords: Marine-derived Aspergillus, metabolites, cytotoxic, antimicrobial, antioxidant, enzymatic activities, structureactivity.

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Article Details

VOLUME: 18
ISSUE: 13
Year: 2018
Page: [1072 - 1094]
Pages: 23
DOI: 10.2174/1389557518666180305160856
Price: $65

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