Recently, the marine-derived Aspergillus present as producers of a large number of structurally
novel secondary metabolites. Some of these metabolites have shown antitumor, antimicrobial,
anti-inflammatory, antioxidant and enzymatic activities, and may be promising resources for new
therapeutic drugs. This review sums up 232 new bioactive metabolites from the marine-derived Aspergillus
with classification through their biological activities and chemical structures in 2006-2016. Besides,
structure-activity relationships of some compounds are explored.
Keywords: Marine-derived Aspergillus, metabolites, cytotoxic, antimicrobial, antioxidant, enzymatic activities, structureactivity.
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