Potentiating Effect of Ethnomedicinal Plants Against Proliferation on Different Cancer Cell Lines

Author(s): Talib Hussain, Shrestha Bajpai, Mohd Saeed, Afrasim Moin, Ahmed Alafnan, Moazzam Khan, Mohammad Amjad Kamal, Magdah Ganash, Ghulam Md. Ashraf*

Journal Name: Current Drug Metabolism

Volume 19 , Issue 7 , 2018

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Graphical Abstract:


Background: There is a long history of traditional medicine for serving the world population. For the prevention and treatment of cancer, herbal remedies have played a significant role. In this review, we have summarized medicinal herbs from the entire world, including India, that are used traditionally for various cancer treatment. Whenever we talk about cancer treatment, medicinal plants always have been on the priority.

Objective: In this article, we have summarized the flora used in earlier times and recently identified for pre-clinical anticancer treatment. The present paper is a comprehensive review of different literature sources with discussion being made on the therapeutic value of diverse medicinal herbs in the treatment of various kinds of cancer by using different in vitro cancer cell lines. Countless anticancer plants have been recognized with the help of innovative techniques including isolation and structure elucidation that implement their beneficial effect by increasing the immunity of the body, inducing antioxidant action, endorsing making of shielding enzymes, hindering cancer triggering enzymes and hormones, and exciting DNA restoration mechanism.

Conclusion: Finally, we have concluded that Argemone mexicana shows maximum anti-cancer activity on various cancer cell lines in comparison to other medicinal plants.

Keywords: Anticancer, medicinal herbs, plant extracts, herbal medicines, MTT assay, cell lines.

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Article Details

Year: 2018
Page: [584 - 595]
Pages: 12
DOI: 10.2174/1389200219666180305144841
Price: $65

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