The optogenetics approach uses a combination of genetic and optical methods to initiate
and control functions in specific cells of biological tissues. Since the high-speed control of neuronal
activity by irradiating channelrhodopsin-2 with blue light was reported in 2005, tremendous advancement
and application of optogenetics in the field of neuroscience, such as in studies that associate neuronal
activity with behaviors, have been initiated. Optogenetics is not only used as a research tool, but
is also started to apply in the diagnosis of a disease or as therapy in various studies. Here, we summarize
reports on therapy using a typical photoreceptor used in optogenetics, channelrhodopsin-2.
Keywords: Optogenetics, Channnelrhodopsin -2, Gene therapy, Neuroscience, Cardiac resynchronization, Insulin, diabetes.
Rights & PermissionsPrintExport