Factors strongly related to the risk of developing diabetic foot infections include vascular, neuropathic
and hyperglycemic complications of long-standing diabetes mellitus. These infections are common and serious,
posing a worldwide burden on administrative providers of healthcare, patients and physicians. The most appropriate
approach to these infections is with a multidisciplinary team. This subchapter summarizes the current state-of the-art concerning therapy, and scientific knowledge, for peripheral arterial insufficiency, hyperglycemia, and
peripheral neuropathy of the diabetic foot, with an emphasis on the infectious complications.
Keywords: Diabetic foot infection, hyperglycemia, ischemia, pain, diabetes mellitus, peripheral neuropathy.
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