Title:One-Pot Strategies for the Synthesis of Nitrogen-Containing Heteroaromatics
VOLUME: 5 ISSUE: 1
Author(s):Magne O. Sydnes*
Affiliation:Department of Mathematics and Natural Science, Faculty of Science and Technology, University of Stavanger, NO-4036 Stavanger
Keywords:Nitrogen-containing heteroaromatics, one-pot reactions, multicomponent reactions, pyrrole, pyridine, indole,
quinolone, isoquinoline, imidazo[1, 2-a]pyridine.
Abstract:Nitrogen-containing heteroaromatics are commonly found in biologically active natural
products, pharmaceuticals, agrochemicals, and functional materials. Naturally, this has resulted in
such heterocycles being popular synthetic targets for many research groups around the world with
numerous methodologies developed for their formation. The preparation of nitrogen-containing heteroaromatics
by using various one-pot strategies has lately become more popular due to the increased
focus on minimizing waste and cutting back on experimental operations. This review will highlight
some of the most recent one-pot strategies used in order to assemble nitrogen containing heteroaromatics
with particular emphasis on methodologies leading to the preparation of pyrroles, pyridines,
indoles, quinolone, isoquinoline, and imidazo[1,2-a]pyridine.
