One-Pot Strategies for the Synthesis of Nitrogen-Containing Heteroaromatics

Author(s): Magne O. Sydnes*

Journal Name: Current Green Chemistry

Volume 5 , Issue 1 , 2018

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Graphical Abstract:


Nitrogen-containing heteroaromatics are commonly found in biologically active natural products, pharmaceuticals, agrochemicals, and functional materials. Naturally, this has resulted in such heterocycles being popular synthetic targets for many research groups around the world with numerous methodologies developed for their formation. The preparation of nitrogen-containing heteroaromatics by using various one-pot strategies has lately become more popular due to the increased focus on minimizing waste and cutting back on experimental operations. This review will highlight some of the most recent one-pot strategies used in order to assemble nitrogen containing heteroaromatics with particular emphasis on methodologies leading to the preparation of pyrroles, pyridines, indoles, quinolone, isoquinoline, and imidazo[1,2-a]pyridine.

Keywords: Nitrogen-containing heteroaromatics, one-pot reactions, multicomponent reactions, pyrrole, pyridine, indole, quinolone, isoquinoline, imidazo[1, 2-a]pyridine.

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Article Details

Year: 2018
Published on: 19 June, 2018
Page: [22 - 39]
Pages: 18
DOI: 10.2174/2213346105666180222122637
Price: $25

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