A wide variety of hydroxyaryl ketones bearing different motifs was successfully synthesized
with good yields and excellent selectivities in the presence of HF@SiO2 as an environmental friendly
acid under solvent-free condition. Mild and green reaction conditions and excellent yields (50-91%)
make this method an attractive method for the efficient synthesis of hydroxyaryl ketones. Fries rearrangement
of phenyl benzoate in the presence of HF@SiO2 led to p-hydroxybenzophenone, while
phenyl acetate in the same conditions produced o-hydroxyacetophenone as a single isomer.
Keywords: Fries rearrangement, hydroxyaryl ketones, HF@SiO2, solvent-free condition, selective synthesis, isomer.
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