Abstract
In this review, we show the life cycle of parabens, commonly used preservatives that exist in nature and commercial products. Typical synthetic methods to produce parabens, and a set of complimentary characterization techniques to monitor the composition of parabens are also highlighted. This includes solid state analysis using Scanning Electron Microscope (SEM), Differential Scanning Calorimetry (DSC) and X-Ray Diffraction (XRD), in-situ monitoring of crystallization process using Focused Beam Reflectance Measurement (FBRM), Particle Vision Measurement (PVM), quantitative detection via High Performance Liquid Chromatography (HPLC), and Gas Chromatography (GC). An improved understanding of the overall physical, biophysical and chemical properties of parabens and their life cycle, summarized in this article, are vital for the safety control and extensive applications of relevant products in food, cosmetic and pharmaceutical industries.
Keywords: Paraben, synthesis, degradation, characterization, safety, analysis.
Current Organic Chemistry
Title:Review on Life Cycle of Parabens: Synthesis, Degradation, Characterization and Safety Analysis
Volume: 22 Issue: 8
Author(s): Huaiyu Yang, Fan Zhang*Han Wu*
Affiliation:
- Department of Chemical Engineering and Science, Royal Institute of Technology KTH, Stockholm,Sweden
- Department of Chemical Engineering, University College London, London,United Kingdom
Keywords: Paraben, synthesis, degradation, characterization, safety, analysis.
Abstract: In this review, we show the life cycle of parabens, commonly used preservatives that exist in nature and commercial products. Typical synthetic methods to produce parabens, and a set of complimentary characterization techniques to monitor the composition of parabens are also highlighted. This includes solid state analysis using Scanning Electron Microscope (SEM), Differential Scanning Calorimetry (DSC) and X-Ray Diffraction (XRD), in-situ monitoring of crystallization process using Focused Beam Reflectance Measurement (FBRM), Particle Vision Measurement (PVM), quantitative detection via High Performance Liquid Chromatography (HPLC), and Gas Chromatography (GC). An improved understanding of the overall physical, biophysical and chemical properties of parabens and their life cycle, summarized in this article, are vital for the safety control and extensive applications of relevant products in food, cosmetic and pharmaceutical industries.
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Cite this article as:
Yang Huaiyu , Zhang Fan *, Wu Han *, Review on Life Cycle of Parabens: Synthesis, Degradation, Characterization and Safety Analysis, Current Organic Chemistry 2018; 22 (8) . https://dx.doi.org/10.2174/1385272822666180123150323
DOI https://dx.doi.org/10.2174/1385272822666180123150323 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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