Purpose: To explore the role of stereotactic body radiotherapy (SBRT) in the
management of primary or metastatic liver cancer.
Materials and Methods: A systematic search of the PubMed database was conducted to
identify indications and patient selection criteria, technique and dose prescription, oncologic
outcomes and side effects of stereotactic body radiotherapy (SBRT) for liver
Results: The role for radiotherapy in the management of liver cancer is increasing,
thanks to recent developments and technological advances in diagnosis, surgery, conformal
radiotherapy, and new chemotherapy regimens. SBRT delivers a conformal high
dose of radiation to the target lesion and a minimal dose to surrounding critical tissues.
Integrated, multidisciplinary management significantly improves overall survival and
quality of life.
Conclusion: Stereotactic body radiation therapy is a non-invasive, effective and welltolerated
treatment modality for patients with liver cancer.