A Clean, Mild, and Efficient Preparation of Aryl 14H-benzo[a,j]xanthene leuco-dye Derivatives Via Nanocatalytic MCM-41-SO3H Under Ultrasonic Irradiation in Aqueous Media

Author(s): Mostafa Fathollahi, Shahnaz Rostamizadeh*, Ali M. Amani

Journal Name: Combinatorial Chemistry & High Throughput Screening
Accelerated Technologies for Biotechnology, Bioassays, Medicinal Chemistry and Natural Products Research

Volume 21 , Issue 1 , 2018

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Aim and Objective: The present study has developed an efficient and eco-friendly protocol for the synthesis of aryl-14-H-dibenzo[a,j] xanthenes through a one-pot condensation reaction of 2-naphthol and arylaldehydes in aqueous media using the nanocatalytic MCM-41-SO3H under ultrasonic illumination.

Material and Methods: Using SEM and XRD analyses, MCM-41-SO3H nanoparticles were characterized. Therefore, for high magnification, taking the SEM image, the mesoporous surface of MCM-41-SO3H nanoparticles coated with gold for 2 minutes was characterized. Moreover, at a scan rate of 0.02° (2Θ)/sec, XRD analysis from 1.5° (2Θ) to 10.0° (2Θ) was performed.

Result: For our considered sample, some well-ordered XRD patterns with one main peak as well as three minor peaks equal to those of MCM-41 materials were observed.

Conclusion: The suggested route demonstrates very promising properties like higher yields, decrease in the time of reaction (5-10 min), mild and straightforward conditions, low level of toxicity, and inclusion of a cost-efficient and ecofriendly catalyst having considerable reusability.

Keywords: Xanthene, leuco-dye, nanocatalyst, MCM-41-SO3H, ultrasonic irradiation, green chemistry.

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Article Details

Year: 2018
Page: [5 - 13]
Pages: 9
DOI: 10.2174/1386207321666180104111508
Price: $65

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