Synthesis of Polyfunctionalized Furans by Three-component Reaction Between Arylglyoxals, 1,3-Diketones and Isocyanides

Author(s): Motahareh Heidari, Mohammad Anary-Abbasinejad*, Dadkhoda Ghazanfari, Mohammad Reza Akhgar

Journal Name: Letters in Organic Chemistry

Volume 15 , Issue 9 , 2018


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Abstract:

Three-component reaction between arylglyoxal monohydrates, isocyanides and 1,3- diketones in water is reported. This reaction provides a simple and efficient route for the synthesis of poly-functionalized furan derivatives. The reaction conditions and work-up procedure are simple and products were obtained in good yields.

Keywords: Arylglyoxal, three-component reaction, furan, isocyanide, 1, 3-diketones, aqueous media.

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Article Details

VOLUME: 15
ISSUE: 9
Year: 2018
Published on: 26 July, 2018
Page: [773 - 777]
Pages: 5
DOI: 10.2174/1570178615666180102143215
Price: $65

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