Lipases - Valuable Biocatalysts in Kinetic Resolution of Racemates

Author(s): Agata Tarczykowska, Adam Sikora, Michal Piotr Marszall*

Journal Name: Mini-Reviews in Organic Chemistry

Volume 15 , Issue 5 , 2018

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Abstract:

This paper describes the importance of lipases as biocatalysts in various organic applications. Additionally, the influence of different immobilization techniques of enzymes on their catalytic activity and operational stability were investigated. There are many factors affecting the effectiveness and stereoselectivity of lipases in reactions of kinetic resolution. However, the optimization of reaction parameters is essential to obtain high yields of enantiopure products.

Keywords: Lipases, biocatalysts, kinetic resolution, racemates, immobilization method, enzyme immobilization.

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Article Details

VOLUME: 15
ISSUE: 5
Year: 2018
Page: [374 - 381]
Pages: 8
DOI: 10.2174/1570193X15666171228145012
Price: $65

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