Title:Drug-Coated Balloons Applications in Interventional Cardiology
VOLUME: 24 ISSUE: 4
Author(s):Gianluca Rigatelli* and Marco Zuin
Affiliation:Section of Cardiovascular Diagnosis and Endoluminal Interventions, Rovigo General Hospital, Rovigo, Department of Cardiology, Rovigo General Hospital, Rovigo, Italy and Section of Internal and Cardiopulmonary Medicine, Department of Medical Science, University of Ferrara, Ferrara
Keywords:Balloon, angioplasty, drug, interventional, anti-proliferative drug delivery, Drug Coated Balloons (DCBs).
Abstract:Backgrounds: Drug coated balloons (DCBs) are new on stented-based anti-proliferative drug delivery
systems, recently introduced in interventional cardiology. Their primary aim is to transfer an anti-proliferative
drug to reduce the subsequent neo-intima hyperplasia and to maintain the normal vessel diameter and function.
Methods: A review of the most recent influential studies about DCBs in all the fields of interventional cardiology
has been performed.
Results: As demonstrated by different studies, DCBs have different theoretical advantages over Drug Eluting
Stents (DESs), especially for the treatment of some endovascular lesions, as In-Stent Restenosis (ISR), coronary
bifurcations, small vessels disease and peripheral artery disease at femoropopliteal and below the knee sites.
Conclusion: Despite the need of further studies are needed to elucidate the optimal use of DCBs their current use
in interventional cardiology appears promising.
