Immunity of Geohelminthiasis and the Effect on Modulation of Autoimmunity and Allergy
Pp. 251-261 (11)
Vlaudia Maria Assis Costa and Valdenia Oliveira Souza
Geohelminths infections are a group of nematodes worms that are
transmitted to human by ingestion of eggs or larvae penetration after contact with
contaminated soil. The main species that infect people are the Ascaris lumbricoides,
Trichuris trichiura, Necator americanus and Ancylostoma duodenale. Geohelminth
infection has been shown to have a significant impact in modulates others pathologies.
These parasites might enhance the survival modulating the immune response of their
host inducing a regulatory response. This chapter is a review of the recent literature
about the host immune response against geohelminths and the potential effect of these
infections on non-parasite immune response.
Allergies, Autoimmunity, Geohelminthiasis, Immunomodulation.
Department of Pharmaceutical Sciences/Keizo Asami Laboratory of Immunopathology – Federal University of Pernambuco, Brazil.