Evaluation of the Nutraceutical and Cosmeceutical Potential of Two Cultivars of Rubus fruticosus L. under Different Cultivation Conditions

Author(s): Maria Papaioanou, Evangelia G. Chronopoulou, Gheorghii Ciobotari, Rodica C. Efrose, Liliana Sfichi-Duke, Marianna Chatzikonstantinou, Evangelia Pappa, Ioannis Ganopoulos, Panagiotis Madesis, Irini Nianiou-Obeidat, Taofen Zeng, Nikolaos E. Labrou*

Journal Name: Current Pharmaceutical Biotechnology

Volume 18 , Issue 11 , 2017

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Graphical Abstract:


Background: The starting point for the development of new, functional products derived from Rubus fruticosus L. is to determine the optimal cultivation conditions that produce maximal yield of fruits containing desirable bioactive properties. Towards that goal, the effect of soil, soil/peat mixture and light intensity on the nutraceutical and cosmeceutical potential of two cultivars (‘Thornfree’ and ‘Loch Ness') of Rubus fruticosus L. were evaluated.

Methods: The assessment was carried out employing a range of methods for evaluating fruit properties associated with promoting good health such as total antioxidant capacity, secondary metabolites content (vitamin C, polyphenols, flavonoids and anthocyanins) and inhibition analysis of skin-regulating enzymes.

Results: ‘Thornfree' cultivar produced fruits in all light conditions, while ‘Loch Ness' did not produce fruits in low light conditions. The results showed that in Rubus fruticosus L. fruit, the chemical composition and bioactivity are strongly affected by both genetics factors and growing conditions. Extract from ‘Thornfree' fruits obtained under low light and soil/peat conditions displayed superior properties such as high antioxidant capacity, high concentrations of phenolics, flavonoids and anthocyanins and high inhibitory potency towards the enzymes tyrosinase and elastase. This extract was used for the development of a topical skin care cream with excellent compatibility and stability.

Conclusion: Our findings conclude that Rubus fruticosus L. cultivation may be efficiently and effectively manipulated through conventional cultivation techniques to produce promising bioactive ingredients with potential use in commercial cosmetics and pharmaceuticals.

Keywords: Anthocyanins, cosmeceuticals, flavonoids, nutraceuticals, polyphenols, Rubus fruticosus.

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Article Details

Year: 2017
Page: [890 - 899]
Pages: 10
DOI: 10.2174/1389201019666171226150750
Price: $65

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