Title:L-Proline Catalyzed Synthesis of Various N-substituted Urea and Unsymmetrical N,N’-disubstituted Urea
VOLUME: 15 ISSUE: 11
Author(s):Ajit G. Nagarkar and Vikas N. Telvekar*
Affiliation:Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai 400 019, Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai 400 019
Keywords:N-substituted urea, urea, amines, N, N`-disubstituted urea, L-Proline, green catalyst.
Abstract:Here, we report a simple and efficient method for the synthesis of different unsymmetrical
N,N’-disubstituted urea and N-substituted urea derivatives using L-Proline as a green catalyst. The
methodology is applicable for synthesizing various derivatives of phenylurea, diphenyl urea with excellent
yield at mild condition.
