L-Proline Catalyzed Synthesis of Various N-substituted Urea and Unsymmetrical N,N’-disubstituted Urea

Title:L-Proline Catalyzed Synthesis of Various N-substituted Urea and Unsymmetrical N,N’-disubstituted Urea

Volume: 15 Issue: 11

Author(s): Ajit G. Nagarkar and Vikas N. Telvekar*

Affiliation:

• Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai 400 019,India

Keywords: N-substituted urea, urea, amines, N, N`-disubstituted urea, L-Proline, green catalyst.

Abstract: Here, we report a simple and efficient method for the synthesis of different unsymmetrical N,N’-disubstituted urea and N-substituted urea derivatives using L-Proline as a green catalyst. The methodology is applicable for synthesizing various derivatives of phenylurea, diphenyl urea with excellent yield at mild condition.

Cite this article as:

Nagarkar G. Ajit and Telvekar N. Vikas *, L-Proline Catalyzed Synthesis of Various N-substituted Urea and Unsymmetrical N,N’-disubstituted Urea, Letters in Organic Chemistry 2018; 15 (11) . https://dx.doi.org/10.2174/1570178615666171212145348