L-Proline Catalyzed Synthesis of Various N-substituted Urea and Unsymmetrical N,N’-disubstituted Urea

Author(s): Ajit G. Nagarkar, Vikas N. Telvekar*

Journal Name: Letters in Organic Chemistry

Volume 15 , Issue 11 , 2018

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Graphical Abstract:


Here, we report a simple and efficient method for the synthesis of different unsymmetrical N,N’-disubstituted urea and N-substituted urea derivatives using L-Proline as a green catalyst. The methodology is applicable for synthesizing various derivatives of phenylurea, diphenyl urea with excellent yield at mild condition.

Keywords: N-substituted urea, urea, amines, N, N`-disubstituted urea, L-Proline, green catalyst.

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Article Details

Year: 2018
Page: [926 - 930]
Pages: 5
DOI: 10.2174/1570178615666171212145348
Price: $65

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